Chronic Chloroform Intoxication

Chronic chloroform intoxication.

Chloroform was discovered in 1831 by a French chemist, Soubeiran, and independently by the American, Samuel Guthrie of Sachett's Harbour, in the State ofNew York (Duncum, 1947). Soubeiran obtained impure chloroform, which he provisionally called " bichloric ether ", by distilling a mixture of chloride of lime and alcohol. Liebig, in the following year, obtained a purer chloroform, which he name...

Prothrombin Deficiency and the Bleeding Tendency in Liver Injury (chloroform Intoxication)

The bleeding tendency in acute chloroform intoxication is due to deficiency in both plasma fibrinogen and plasma prothrombin. If the disorder is mild, no bleeding occurs. However, the prothrombin falls to rather low levels, although the fibrinogen falls only moderately. A bleeding tendency may also be produced by giving small repeated doses of chloroform. In such experiments, the hemorrhagic te...

Chronic lead intoxication mimicking motor neurone disease.

a sexual contact by gonorrhoea patients is a valid candidate for the procedure known as " epidemiologic treatment " even when cultures (which may miss 20%, or more of such gonococcal infections) are negative. If chemotherapy is adequate, a link in a chain of infection may thus be broken. A patient who would refuse a diagnosis of venereal disease may willingly accept this precautionary measure, ...

[Aluminium intoxication in chronic kidney disease].

Chronic Arsenic Intoxication in Asia: Current Perspectives

Chronic arsenic intoxication has been an issue of public health concern in some countries in Asia, such as Taiwan, Mainland China, Bangladesh, India, and Thailand. In Taiwan, an endemic peripheral vascular disease known as ‘blackfoot disease’ (BFD) located in a confined area along the southwestern coast of Taiwan attracted the attention of the government and the scientific professionals since m...